Are Your Medications Contributing to Dry Eye Disease? Medications are one of the most common contributors to dry eye disease. In some cases, medications can reduce tear production, affect the quality of the tear film, or increase inflammation on the surface of the eyes, leading to symptoms of dryness, irritation, burning, fluctuating vision or excessive tearing. Because dry eye disease is often multifactorial, medications may worsen existing symptoms or even uncover dry eye p